AGO2 [FBgn0087035]

gene

AGO2

ID: FBgn0087035

Gene

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Classification

gene

Relationships

enables: endoribonuclease activity, cleaving siRNA-paired mRNA (PMID:30308158)
enables: miRNA binding (GO_REF:0000033)
enables: protein binding (PMID:11498593)
enables: single-stranded RNA binding (PMID:30590701)
enables: siRNA binding (PMID:30590701)
is part of: ALTERNATIVE siRNA RISC-LOADING COMPLEX, ARGONAUTE ENDORIBONUCLEASES, siRNA RISC-LOADING COMPLEX

Alternative Names

Synonym	Scope	Reference
AGO 2	exact synonym
Argonaute2	exact synonym
Argonaute 2	exact synonym
Argonaute-2	exact synonym
argonaute-2	exact synonym
ago	exact synonym
AG02	exact synonym
ago-2	exact synonym
CG7439	exact synonym
Ago2a	exact synonym
Ago-2	exact synonym
argonaute 2	exact synonym
dAGO2	exact synonym
AGO-2	exact synonym
Argonaute	exact synonym
ago2	exact synonym
ARGONAUTE2	exact synonym
AGO2	exact synonym
argonaute	exact synonym
Dm Ago2	exact synonym
AGO1	exact synonym
Ago2	exact synonym
argonaute2	exact synonym
DmAgo2	exact synonym
CG13452	exact synonym
eIF2C2	exact synonym
dAgo2	exact synonym

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"iri": "http://purl.obolibrary.org/obo/GO_0003727", "types": [ "Entity", "Class" ], "short_form": "GO_0003727", "label": "single-stranded RNA binding" } }, { "relation": { "iri": "http://purl.obolibrary.org/obo/RO_0002327", "label": "enables", "type": "enables" }, "object": { "symbol": "", "iri": "http://purl.obolibrary.org/obo/GO_0005515", "types": [ "Entity", "Class" ], "short_form": "GO_0005515", "label": "protein binding" } }, { "relation": { "iri": "http://purl.obolibrary.org/obo/RO_0002327", "label": "enables", "type": "enables" }, "object": { "symbol": "", "iri": "http://purl.obolibrary.org/obo/GO_0035198", "types": [ "Entity", "Class" ], "short_form": "GO_0035198", "label": "miRNA binding" } }, { "relation": { "iri": "http://purl.obolibrary.org/obo/RO_0002327", "label": "enables", "type": "enables" }, "object": { "symbol": "", "iri": "http://purl.obolibrary.org/obo/GO_0035197", "types": [ "Entity", "Class" ], "short_form": "GO_0035197", "label": "siRNA binding" } }, { "relation": { "iri": "http://purl.obolibrary.org/obo/RO_0002327", "label": "enables", "type": "enables" }, "object": { "symbol": "", "iri": "http://purl.obolibrary.org/obo/GO_0070551", "types": [ "Entity", "Class" ], "short_form": "GO_0070551", "label": "endoribonuclease activity, cleaving siRNA-paired mRNA" } }, { "relation": { "iri": "http://purl.obolibrary.org/obo/BFO_0000050", "label": "is part of", "type": "part_of" }, "object": { "symbol": "", "iri": "http://flybase.org/reports/FBgg0001553", "types": [ "Entity", "Class" ], "short_form": "FBgg0001553", "label": "ALTERNATIVE siRNA RISC-LOADING COMPLEX" } }, { "relation": { "iri": "http://purl.obolibrary.org/obo/BFO_0000050", "label": "is part of", "type": "part_of" }, "object": { "symbol": "", "iri": "http://flybase.org/reports/FBgg0001552", "types": [ "Entity", "Class" ], "short_form": "FBgg0001552", "label": "siRNA RISC-LOADING COMPLEX" } }, { "relation": { "iri": "http://purl.obolibrary.org/obo/BFO_0000050", "label": "is part of", "type": "part_of" }, "object": { "symbol": "", "iri": "http://flybase.org/reports/FBgg0001778", "types": [ "Entity", "Class" ], "short_form": "FBgg0001778", "label": "ARGONAUTE ENDORIBONUCLEASES" } } ], "xrefs": [], "anatomy_channel_image": [], "pub_syn": [ { "synonym": { "scope": "has_exact_synonym", "label": "argonaute", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "ago-2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "Argonaute2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "eIF2C2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "AGO1", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "Dm Ago2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "Ago2a", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "argonaute2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "CG7439", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "ARGONAUTE2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "Ago-2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "AG02", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "DmAgo2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "Argonaute-2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "argonaute 2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "argonaute-2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "CG13452", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "AGO2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "Ago2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "ago2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "ago", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "dAGO2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "Argonaute", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "AGO 2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "Argonaute 2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "dAgo2", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } } ], "def_pubs": [] }

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